THERAPY

DR. MAL

1.1ml / 0.037 fl.oz. x 27 vials

100ml / 3.4 fl.oz. x Cleanser

Dr. MAL consists of MAL (Methyl Aminolevulinate HCI) ingredients, used for photodynamic therapy (PDT).

As a therapy that destroys sebum and inflammation, which are the fundamental causes of troubled skin, it effectively manages troubled skin and helps recover skin conditions.

PRINCIPLE

01 When a pore with inflammation absorbs the Dr.MAL (Methyl ALA), it is transformed into Pplx.

02 Photodynamic Therapy refers to the process of irradiating the light energy of a certain wavelength, followed by the application of a photosensitizer, which selectively permeates into the sebaceous glands and pores, on skin. It helps improve troubled skin.

03 As the light of a certain wavelength is irradiated, it destroys acne bacteria and sebaceous glands resulting in the reduced inflammation.

MAININGREDIENTS

METHYL - ALA 13%

PANAX GINSENG CALLUS CULTURE EXTRACT

WHATISDR.MAL

WHY DR. MAL?

Methyl-ALA (MAL) minimizes the skin damage, pain which may occur during PDT. According to the reports by Wiegell and Wulf, MAL is reported to cause less pain, compared to ALA, while simultaneously having a short post-treatment waiting time with reduced PDT side effects, hence proven to be effective for treatment.

HIGH SATISFACTION LEVEL

MAL, which consists of methyl derivative bound to ALA, shows greater prognosis than the existing ALA.
MAL-PDT showed a significantly greater effect in the improvement of troubled skin conditions when compared to ALA-PDT.

*Median reduction in numbers of inflammatory lesion counts from baseline.

SHORT INCUBATION TIME 25-30MIN

Methyl-ALA (MAL) is oil-soluble, hence has a greater skin absorption rate when compared to the existing ALA.
The higher the level of concentration of MAL, the greater the amount of Porphyrins that are absorbed by the skin. Hence, the amount of Porphyrins absorbed is proportionate to the level of concentration of MAL.

Depth of porphyrin fluorescence in lesions

*Number of subjects measured.

MINIMIZED CELL DAMAGE

As the amount of Porphyrins absorbed within the healthy cells of MAL (1.7nmol/g) is lower than that of ALA (7.2nmol/g) approximately by 1/7, the skin damage caused by MAL-PDT could be considered to be less than the damage caused by ALA-PDT.

Porphyrip levels and distribution of prophyrin metabolites 6h after substrate application*

POST DR.MAL CLEANSER INCLUDED

MAL Neutralizing solution inhibits the conversion into Pplx by neutralizing the remaining MAL and ALA on the skin surface.*
Post-Dr. MAL Cleanser minimizes the side effects that may be caused from the ALA remaining on skin.

In case of using Methyl-ALA, merely conducting the LED irradiation leads to the same effects by IPL

HOWTOUSE

1 PREPARATION

1. Cleansing

Peeling helps the absorption of Dr. MAL

2. Acne Extraction

2 PHOTO DYNAMIC THERAPY

1. Application of Dr. MAL

1 vial

2. Incubation 20-25 min

The process in which the MAL absorbed by skin binds with inflammatory cells and sebaceous cells. Prevent light by covering the entire face with a wrap then covering it with blackout towel.

3. Removal
of remaining Dr. MAL

Cleanse the areacompletely using a cleansing sponge

4. LED Irradiation 15-20 min
(RED Light 630nm)

PDT reaction; Absorbed Dr.MAL solution meets the LED Light source.

FINISHING

3

1. Post - Dr. MAL cleanser

(3-5 times pumping) Post-Dr.Mal helps decompose the solution remaining on the skin surface. Gently rub with fingers for 3-5 minutes. It prevents tanning which could occur after PDT reaction.